Failure is far from a given for those who undergo meniscal allograft transplantation (MAT). In what is the largest series in the literature, Brian Cole, M.D. and colleagues have just this week published information indicating positive results for those undergoing meniscal allograft transplantation.
Dr. Cole, Professor in the Departments of Orthopaedic Surgery and Anatomy & Cell Biology at Rush University Medical Center, told OTW, “We looked at 200 patients who underwent MAT, 172 of whom were evaluated at 59 months with a minimum two year follow-up. Sixty-percent of these patients had a combined MAT with a concomitant articular cartilage procedure such as an osteochondral allograft.
Our goal was to determine the indications for a second surgery after a meniscal transplant, as well as what would be likely to happen if people required a second surgery. Thirty-two percent required a second operation (due to scar tissue and/or persistent symptoms).” “There was a 95% allograft survival rate at five years; even those who had to undergo a second surgery fared well with an 88% survival rate (however they were at a slight increased risk of failure).
This news helps us as far as educating people in this complicated patient group. These are typically individuals who have undergone multiple operations; our study helps us to better understand what the future looks like for these patients. We can now say to patients, ‘Even if you undergo a meniscal allograft transplant—with or without a subsequent arthroscopic surgery—it doesn’t mean it is going to fail.” [read complete article]